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xenotransplantation

Explore xenotransplantation - transplanting organs from genetically modified pigs to humans. Learn about CRISPR gene editing, immune rejection, and how this technology could solve the organ shortage crisis.

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🎯 模拟器提示

📚 术语表

Xenotransplantation
不同物种之间的移植
AlphaGal
猪糖分子引起超急性排斥反应
CRISPR
基因编辑工具修改猪基因组
Knockout
从基因组中删除基因
Knockin
将基因添加到基因组中
HyperacuteRejection
立即免疫攻击(分钟)
AcuteRejection
早期免疫攻击(数天至数周)
PERV
猪内源性逆转录病毒
Complement
攻击外来细胞的免疫系统蛋白质
Immunosuppression
降低免疫系统活性的药物

🏆 关键人物

David Bennett Sr.

Muhammad Mohiuddin

领导马里兰大学异种移植项目

George Church

CRISPR 先驱,eGenesis 联合创始人

Luhan Yang

eGenesis 猪基因编辑公司首席执行官

💬 给学习者的话

{'encouragement': "You're learning about medicine at the frontier - technology that could eliminate the organ shortage and save hundreds of thousands of lives. Xenotransplantation is happening NOW, not in the distant future.", 'reminder': 'The first pig heart transplants have already occurred. Clinical trials are underway. This is real medicine being developed in real time.', 'action': 'Edit pig genes in the simulator. See how different modifications affect rejection. Understand the immune challenges being overcome.', 'dream': 'A surgeon from Kenya might perform xenotransplants that save lives across Africa. A geneticist from Nigeria might improve pig organ compatibility. The organ shortage is a global problem needing global solutions.', 'wiaVision': 'WIA Pin Code believes life-saving medical knowledge should reach everyone. Xenotransplantation could transform medicine in regions where donor organs are especially scarce.'}

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