xenotransplantation

¿Qué es esto?

🎯 Consejos del simulador

📚 Glosario

Xenotransplantation

Trasplante entre diferentes especies.

AlphaGal

Molécula de azúcar de cerdo que provoca rechazo hiperagudo

CRISPR

Herramienta de edición genética para modificar el genoma del cerdo

Knockout

Eliminar un gen del genoma

Knockin

Agregar un gen al genoma

HyperacuteRejection

Ataque inmunológico inmediato (minutos)

AcuteRejection

Ataque inmune temprano (días-semanas)

PERV

Retrovirus endógenos porcinos

Complement

Proteínas del sistema inmunológico que atacan a las células extrañas.

Immunosuppression

Medicamentos para reducir la actividad del sistema inmunológico.

🏆 Figuras clave

David Bennett Sr.

Muhammad Mohiuddin

Lideró el programa de xenotrasplantes de la Universidad de Maryland

George Church

Pionero de CRISPR, cofundador de eGenesis

Luhan Yang

CEO de eGenesis, edición de genes porcinos

💬 Mensaje a los estudiantes

{'encouragement': "You're learning about medicine at the frontier - technology that could eliminate the organ shortage and save hundreds of thousands of lives. Xenotransplantation is happening NOW, not in the distant future.", 'reminder': 'The first pig heart transplants have already occurred. Clinical trials are underway. This is real medicine being developed in real time.', 'action': 'Edit pig genes in the simulator. See how different modifications affect rejection. Understand the immune challenges being overcome.', 'dream': 'A surgeon from Kenya might perform xenotransplants that save lives across Africa. A geneticist from Nigeria might improve pig organ compatibility. The organ shortage is a global problem needing global solutions.', 'wiaVision': 'WIA Pin Code believes life-saving medical knowledge should reach everyone. Xenotransplantation could transform medicine in regions where donor organs are especially scarce.'}