longevity-algorithm

What is this?

🎯 Simulator Tips

📚 Glossary

Healthspan

Years of healthy, functional life

Lifespan

Total years of life

Senescence

Cellular aging - cells stop dividing

Senolytics

Drugs that kill senescent cells

Telomere

Protective cap at chromosome ends

Telomerase

Enzyme that extends telomeres

Epigenetic

Changes to gene expression, not DNA sequence

mTOR

Master growth regulator pathway

AMPK

Energy-sensing pathway

Sirtuins

Proteins involved in longevity

NAD+

Critical coenzyme that declines with age

Autophagy

Cellular self-cleaning process

Inflammaging

Chronic low-grade inflammation with age

🏆 Key Figures

Aubrey de Grey

SENS damage repair framework

David Sinclair

Information theory of aging, sirtuins

Cynthia Kenyon

Discovered longevity genes in C. elegans

Steve Horvath

Epigenetic aging clocks

Shinya Yamanaka

Cellular reprogramming (Nobel Prize)

💬 Message to Learners

{'encouragement': "You're learning about one of humanity's oldest dreams - extending healthy life. For the first time in history, we understand enough about aging to actually do something about it.", 'reminder': 'The best longevity interventions available today are free: exercise, good sleep, healthy diet, stress management. Start there while waiting for future breakthroughs.', 'action': "Explore the hallmarks of aging in the simulator. See how they're interconnected. Understand why targeting multiple pathways matters.", 'dream': 'A biologist from Kenya might discover the next longevity pathway. A computational scientist from Nigeria might create better aging clocks. Longevity research should benefit all of humanity.', 'wiaVision': "WIA Pin Code believes the science of healthy aging should be accessible to everyone. Whether you're 20 or 80, understanding aging empowers better choices."}