🔬

crispr-gene-editor

Learn CRISPR-Cas9 gene editing through interactive simulation. Design guide RNAs, edit DNA sequences, and understand how this Nobel Prize-winning technology is transforming medicine.

🔬 立即試用

這是什麼?

🎯 模擬器提示

📚 術語表

CRISPR
聚集的規則間隔的短回文重複
Cas9
CRISPR 相關蛋白 9 - 切割酶
GuideRNA
引導 Cas9 定位目標 DNA 序列的 RNA
PAM
原型間隔子相鄰基序 - Cas9 結合所需的序列
DoubleStrandBreak
切斷兩條 DNA 鏈
NHEJ
非同源末端連接 - 容易出錯的 DNA 修復
HDR
同源定向修復 - 使用模板進行精確修復
OffTarget
基因組位置錯誤的意外切割
Knockout
禁用基因
Knockin
插入新DNA
SomaticEditing
編輯身體細胞(非遺傳)
GermlineEditing
編輯生殖細胞(遺傳)

🏆 關鍵人物

Jennifer Doudna

共同開發用於基因組編輯的 CRISPR-Cas9

Emmanuelle Charpentier

共同開發CRISPR-Cas9

Feng Zhang

首次在人類細胞中使用 CRISPR

David Liu

發明鹼基編輯與底物編輯

Francisco Mojica

在細菌中發現 CRISPR 序列

🎓 學習資源

💬 給學習者的話

{'encouragement': "You're learning about technology that won the Nobel Prize and is already curing genetic diseases. CRISPR is one of the most important discoveries of our time.", 'reminder': 'With great power comes great responsibility. Gene editing can cure disease, but must be used wisely.', 'action': 'Design a guide RNA in the simulator. See how precise gene editing works. Imagine the diseases you could cure.', 'dream': 'A scientist in Kenya might cure sickle cell disease that affects millions in Africa. A researcher in India might develop disease-resistant crops. This technology is for everyone.', 'wiaVision': 'WIA Pin Code brings Nobel Prize-winning biotechnology to everyone. The power to edit genes is now accessible. Learn it. Use it responsibly. Change the world.'}

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