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crispr-gene-editor

Learn CRISPR-Cas9 gene editing through interactive simulation. Design guide RNAs, edit DNA sequences, and understand how this Nobel Prize-winning technology is transforming medicine.

🔬 立即试用

这是什么?

🎯 模拟器提示

📚 术语表

CRISPR
聚集的规则间隔的短回文重复
Cas9
CRISPR 相关蛋白 9 - 切割酶
GuideRNA
引导 Cas9 定位目标 DNA 序列的 RNA
PAM
原型间隔子相邻基序 - Cas9 结合所需的序列
DoubleStrandBreak
切断两条 DNA 链
NHEJ
非同源末端连接 - 容易出错的 DNA 修复
HDR
同源定向修复 - 使用模板进行精确修复
OffTarget
基因组位置错误的意外切割
Knockout
禁用基因
Knockin
插入新DNA
SomaticEditing
编辑身体细胞(非遗传)
GermlineEditing
编辑生殖细胞(遗传)

🏆 关键人物

Jennifer Doudna

共同开发用于基因组编辑的 CRISPR-Cas9

Emmanuelle Charpentier

共同开发CRISPR-Cas9

Feng Zhang

首次在人类细胞中使用 CRISPR

David Liu

发明碱基编辑和底物编辑

Francisco Mojica

在细菌中发现 CRISPR 序列

🎓 学习资源

💬 给学习者的话

{'encouragement': "You're learning about technology that won the Nobel Prize and is already curing genetic diseases. CRISPR is one of the most important discoveries of our time.", 'reminder': 'With great power comes great responsibility. Gene editing can cure disease, but must be used wisely.', 'action': 'Design a guide RNA in the simulator. See how precise gene editing works. Imagine the diseases you could cure.', 'dream': 'A scientist in Kenya might cure sickle cell disease that affects millions in Africa. A researcher in India might develop disease-resistant crops. This technology is for everyone.', 'wiaVision': 'WIA Pin Code brings Nobel Prize-winning biotechnology to everyone. The power to edit genes is now accessible. Learn it. Use it responsibly. Change the world.'}

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